LEQ506

Catalog No.: A20941

Smo inhibitor

LEQ506

LEQ506 Chemical Structure

CAS NO. 1204975-42-7

LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.

Availability: In stock

Package Price Qty
1 mg
$676.00
5 mg
$2,028.00
10 mg
$3,455.00
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Biological Activity

LEQ506 is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.12 mL 115.59 mL 231.18 mL
0.5 mM 4.62 mL 23.12 mL 46.24 mL
1 mM 2.31 mL 11.56 mL 23.12 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A20941
Actions Inhibitor
CAS No. 1204975-42-7
Formula C25H32N6O
M. Wt 432.56
Purity >98%
Synonyms NVP-LEQ506, LEQ 506, LEQ-506
SMILES OC(C)(C)C1=NC=C(N2[[email protected]](C)CN(C3=NN=C(CC4=CC=CC=C4)C(C)=C3C)CC2)N=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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