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Aromatase inhibitor

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Catalog No. A10523

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Letrozole 10mg A10523-10

Regular Price: €19.00

Special Price: €17.10

Letrozole 50mg A10523-50

Regular Price: €47.50

Special Price: €42.75

Letrozole 100mg A10523-100

Regular Price: €76.00

Special Price: €68.40

Letrozole 10mM * 1mL in DMSO A10523-10mM-D

Regular Price: €61.75

Special Price: €55.58

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.)


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Publications citing Adooq Products
Letrozole Citations (1)
  • WEI LIU, .et al. Randomized controlled trial comparing letrozole with laparoscopic ovarian drilling in women with clomiphene citrate-resistant polycystic ovary syndrome, Exp Ther Med, 2015, Oct; 10(4): 1297-1302 PMID: 26622481

Chemical Information

Catalog Num A10523
Actions Inhibitor
M. Wt 285.3
Formula C17H11N5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 112809-51-5
Synonyms CGS 20267, Femara, Piroxicam

Biological Activity

Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1–3 μg/kg p.o.)
Aromatase (Cell-free assay)
0.07 nM-20 nM


Solubility (25°C) * In vitro DMSO 57 mg/mL (199.78 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 0.5% CMC 10 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 35.05 mL 175.25 mL 350.51mL
0.5 mM 7.01 mL 35.05 mL 70.1 mL
1 mM 3.51 mL 17.53 mL 35.05 mL
5 mM 0.7 mL 3.51 mL 7.01 mL

*The above data is based on the productmolecular weight 285.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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