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Leu13-Motilin

Catalog No.: A61946
Motilin Analogue
[Leu13]-Motilin is a motilin analogue that primarily targets motilin receptors. This compound promotes gastrointestinal motility by inducing concentration-dependent contractions in various segments of the gastrointestinal tract, including the gastric antrum, duodenum, jejunum, ileum, and descending colon. [Leu13]-Motilin is utilized in research to explore the mechanisms of gut motility and to investigate potential therapeutic applications in gastrointestinal disorders.
[Leu13]-Motilin 59530-69-7 Motilin Analogue
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Description[Leu13]-Motilin is a motilin analogue that primarily targets motilin receptors. This compound promotes gastrointestinal motility by inducing concentration-dependent contractions in various segments of the gastrointestinal tract, including the gastric antrum, duodenum, jejunum, ileum, and descending colon. [Leu13]-Motilin is utilized in research to explore the mechanisms of gut motility and to investigate potential therapeutic applications in gastrointestinal disorders.
Product Information
Catalog NumA61946
FormulaC121H190N34O35
Molecular Weight2681.01
CAS Number59530-69-7
SequencePhe-Val-Pro-Ile-Phe-Thr-Tyr-Gly-Glu-Leu-Gln-Arg-Leu-Gln-Glu-Lys-Glu-Arg-Asn-Lys-Gly-Gln
Sequence shorteningFVPIFTYGELQRLQEKERNKGQ
SMILESC([C@@H](NC([C@H](CC1=CC=CC=C1)N)=O)C(C)C)(=O)N2[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@@H](CC4=CC=C(O)C=C4)C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@@H](CCC(N)=O)C(O)=O)=O)=O)CCCCN)=O)CC(N)=O)=O)CCCNC(=N)N)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCCNC(=N)N)=O)CCC(N)=O)=O)CC(C)C)=O)CCC(O)=O)=O)=O)=O)[C@@H](C)O)=O)=O)[C@H](CC)C)=O)CCC2
SynonymsKW-5139
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GPCR/G Protein > Motilin Receptor (MLNR)