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Calcium Folinate, Pentahydrate supplies cells with tetrahydrofolate and diminishes methotrexate toxicity without abolishing antitumor effect.
Targets
| thymidylate synthase | ||||
| In vitro | DMSO | Insoluble | |
| Water | Warmed: 11 mg/mL (18.28 mM) | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.62 mL | 83.11 mL | 166.23 mL |
| 0.5 mM | 3.32 mL | 16.62 mL | 33.25 mL |
| 1 mM | 1.66 mL | 8.31 mL | 16.62 mL |
| 5 mM | 0.33 mL | 1.66 mL | 3.32 mL |
*The above data is based on the productmolecular weight 601.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10524 |
|---|---|
| CAS No. | 6035-45-6 |
| Formula | C20H21CaN7O7 5H2O |
| M. Wt | 601.58 |
| Solubility | DMSO |
| Purity | >98% |
| Synonyms | Folinic acid calcium salt |
| SMILES | C1C(N(C2=C(N1)NC(=NC2=O)N)C=O)CNC3=CC=C(C=C3)C(=O)NC(CCC(=O)[O-])C(=O)[O-].O.O.O.O.O.[Ca+2] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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