Leukotriene F4

Catalog No.: A61011
Arachidonic Metabolite
Leukotriene F4 (LTF4) is an arachidonic metabolite that belongs to the Cysteinyl Leukotriene (CysTL) family. It is known to induce bronchoconstriction, exhibiting an ED50 of 16 μg/kg, which underscores its role in respiratory pathophysiology. LTF4 is generated from its precursor, Leukotriene E4 (LTE4), through the action of a glutamyl transferase. Its biological activity makes it a relevant target for research on inflammatory and respiratory conditions.
Grouped product items
Size Price Stock Qty
25µg
$385.00
In stock
50µg
$715.00
In stock
100µg
$1,345.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
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Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLeukotriene F4 (LTF4) is an arachidonic metabolite that belongs to the Cysteinyl Leukotriene (CysTL) family. It is known to induce bronchoconstriction, exhibiting an ED50 of 16 μg/kg, which underscores its role in respiratory pathophysiology. LTF4 is generated from its precursor, Leukotriene E4 (LTE4), through the action of a glutamyl transferase. Its biological activity makes it a relevant target for research on inflammatory and respiratory conditions.
Product Information
Catalog NumA61011
FormulaC28H44N2O8S
Molecular Weight568.72
CAS Number83851-42-7
SMILESO=C(O)[C@H](CS[C@@H]([C@@H](O)CCCC(O)=O)/C=C/C=C/C=C\C/C=C\CCCCC)NC(CC[C@@H](C(O)=O)N)=O
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