LIT-001 free base

Catalog No.: A62787
Oxytocin Receptor Agonist
LIT-001 free base is a selective oxytocin receptor agonist, exhibiting an EC50 of 55 nM and a Ki of 226 nM. This compound has demonstrated significant enhancement of social interaction behaviors in mouse models of autism, making it a valuable tool for research in neuropsychiatric disorders and social behavior. Its nonpeptide structure distinguishes it as a lead candidate for further investigation into therapeutic applications related to oxytocin signaling.
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLIT-001 free base is a selective oxytocin receptor agonist, exhibiting an EC50 of 55 nM and a Ki of 226 nM. This compound has demonstrated significant enhancement of social interaction behaviors in mouse models of autism, making it a valuable tool for research in neuropsychiatric disorders and social behavior. Its nonpeptide structure distinguishes it as a lead candidate for further investigation into therapeutic applications related to oxytocin signaling.
Product Information
Catalog NumA62787
FormulaC28H33N7O2S
Molecular Weight531.67
CAS Number2245072-20-0
SMILESO=C(N1[C@H](C(N(C)C)=S)CCC1)NCC2=CC=C(C(N3CC4=C(N(C)N=C4)NC5=CC=CC=C35)=O)C=C2C
Useful Calculator

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