LJH685

Catalog No.: A14372

pan-RSK inhibitor

LJH685

LJH685 Chemical Structure

CAS NO. 1627710-50-2

LJH685 is a potent , specific and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50 of 4 to 13 nM.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$150.00
25 mg
$300.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LJH685 is a potent , specific and selective RSK inhibitor, inhibits RSK1, 2, and 3 biochemical activities with IC50 of 4 to 13 nM.
Targets
RSK3 RSK2 RSK1
4 nM5 nM6 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.22 mL 131.09 mL 262.18 mL
0.5 mM 5.24 mL 26.22 mL 52.44 mL
1 mM 2.62 mL 13.11 mL 26.22 mL
5 mM 0.52 mL 2.62 mL 5.24 mL

*The above data is based on the productmolecular weight 381.42. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A14372
Actions Inhibitor
M. Wt 381.42
Formula C22H21F2N3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1627710-50-2
Synonyms LJH 685, LJH-685
SMILES CN(CC1)CCN1C(C=C2)=CC=C2C3=CC=NC=C3C4=CC(F)=C(O)C(F)=C4

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