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Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.66 mL | 63.3 mL | 126.61 mL |
| 0.5 mM | 2.53 mL | 12.66 mL | 25.32 mL |
| 1 mM | 1.27 mL | 6.33 mL | 12.66 mL |
| 5 mM | 0.25 mL | 1.27 mL | 2.53 mL |
*The above data is based on the productmolecular weight 789.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A16600 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 789.83 |
| Formula | C40H41F6N3O5S |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 202914-84-9 |
| Synonyms | AEGR-733 mesylate, AEGR733, AEGR 733; BMS-201038 mesylate, BMS 201038, BMS201038 |
| SMILES | O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F.O=S(C)(O)=O |
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