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Catalog No.: A12778

MTP inhibitor


Lomitapide Chemical Structure

CAS NO. 182431-12-5

Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor.

Availability: In stock

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5 mg
10 mg
25 mg
10mM * 1mL in DMSO
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Julien Allard, .et al. Drug-induced Hepatic Steatosis in Absence of Severe Mitochondrial Dysfunction in HepaRG Cells: Proof of Multiple Mechanism-Based Toxicity, Cell Biol Toxicol, 2020, Jun 14 PMID: 32535746

Biological Activity

Lomitapide is a potent microsomal triglyceride transfer protein (MTP) inhibitor.
In vitro DMSO 97 mg/mL (140.03 mM)
Water Insoluble
Ethanol Warmed: 97 mg/mL (140.03 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.44 mL 72.18 mL 144.36 mL
0.5 mM 2.89 mL 14.44 mL 28.87 mL
1 mM 1.44 mL 7.22 mL 14.44 mL
5 mM 0.29 mL 1.44 mL 2.89 mL

*The above data is based on the productmolecular weight 692.71. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12778
Actions Inhibitor
CAS No. 182431-12-5
Formula C39H37F6N3O2
M. Wt 692.71
Purity >98%
Synonyms 0

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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