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Lp-PLA2 -IN-1 inhibit Lp-PLA2 activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases associated with the activity of Lp-PLA2, for example atherosclerosis, Alzheimer's disease.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 21.35 mL | 106.75 mL | 213.5 mL |
| 0.5 mM | 4.27 mL | 21.35 mL | 42.7 mL |
| 1 mM | 2.14 mL | 10.68 mL | 21.35 mL |
| 5 mM | 0.43 mL | 2.14 mL | 4.27 mL |
*The above data is based on the productmolecular weight 468.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A12168 |
|---|---|
| M. Wt | 468.38 |
| Formula | C21H17F5N4O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1420367-28-7 |
| SMILES | CN1C(N2CCC1)=CC(OCC3=CC(F)=C(OC4=CC=C(C(F)(F)F)N=C4)C(F)=C3)=NC2=O |
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