Lp-PLA2-IN-14

Catalog No.: A77191
Lp-PLA2 Inhibitor
Lp-PLA2-IN-14 is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with a pIC50 of 8.4 against recombinant human Lp-PLA2. This compound demonstrates significant potential in the study of neurodegenerative diseases, such as Alzheimer’s disease, glaucoma, and age-related macular degeneration, as well as cardiovascular conditions, including atherosclerosis. Lp-PLA2-IN-14 serves as a useful tool for researchers investigating the role of Lp-PLA2 in these pathologies.
Grouped product items
Size Price Stock Qty
25mg
$1,275.00
In stock
50mg
$1,625.00
In stock
100mg
$2,000.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

Loading distributor info...

Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLp-PLA2-IN-14 is an inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with a pIC50 of 8.4 against recombinant human Lp-PLA2. This compound demonstrates significant potential in the study of neurodegenerative diseases, such as Alzheimer’s disease, glaucoma, and age-related macular degeneration, as well as cardiovascular conditions, including atherosclerosis. Lp-PLA2-IN-14 serves as a useful tool for researchers investigating the role of Lp-PLA2 in these pathologies.
Product Information
Catalog NumA77191
FormulaC16H14F3N3O3
Molecular Weight353.30
CAS Number2756855-66-8
SMILESO=C1N=C(C2=C(N1CCC3)N3CCO2)OCC4=CC(F)=C(C(F)=C4)F
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2