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Lp-PLA2-IN-15

Catalog No.: A77190
Lp-PLA2 Inhibitor
Lp-PLA2-IN-15 is a selective inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). This compound exhibits potent inhibitory activity, making it valuable for investigating the role of Lp-PLA2 in various biological processes. It is particularly relevant in Alzheimer's disease research and other studies related to inflammation and lipid metabolism.
Lp-PLA2-IN-15 1865796-11-7 Lp-PLA2 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLp-PLA2-IN-15 is a selective inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). This compound exhibits potent inhibitory activity, making it valuable for investigating the role of Lp-PLA2 in various biological processes. It is particularly relevant in Alzheimer's disease research and other studies related to inflammation and lipid metabolism.
Product Information
Catalog NumA77190
FormulaC22H17F5N4O3
Molecular Weight480.39
CAS Number1865796-11-7
SMILESO=C1N2C(N3[C@](CCC3)([H])C2)=CC(OCC4=CC(F)=C(C(F)=C4)OC5=CC=NC(C(F)(F)F)=C5)=N1
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This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Metabolism > Phospholipases