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Lp-PLA2-IN-17

Catalog No.: A77169
Lp-PLA2 Inhibitor
Lp-PLA2-IN-17 is a selective inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). This compound is utilized in research to investigate the role of Lp-PLA2 in the hydrolysis of oxidized lipids, leading to the production of inflammatory mediators. Lp-PLA2-IN-17 is valuable in studying various inflammatory disorders and cardiovascular diseases linked to lipid metabolism.
Lp-PLA2-IN-17 1818842-74-8 Lp-PLA2 Inhibitor
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLp-PLA2-IN-17 is a selective inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2). This compound is utilized in research to investigate the role of Lp-PLA2 in the hydrolysis of oxidized lipids, leading to the production of inflammatory mediators. Lp-PLA2-IN-17 is valuable in studying various inflammatory disorders and cardiovascular diseases linked to lipid metabolism.
Product Information
Catalog NumA77169
FormulaC24H14Cl2F3N5O2
Molecular Weight532.30
CAS Number1818842-74-8
SMILESFC(F)(C1=CC(OC2=CC=C(COC3=NC4=NC=C(N4C=C3)C5=CN=CN=C5)C=C2Cl)=CC=C1Cl)F
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Metabolism > Phospholipases