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Lp-PLA2-IN-2

Catalog No.: A77155
Lp-PLA2 Inhibitor
Lp-PLA2-IN-2 is a potent and selective inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), exhibiting an IC50 of 120 nM for recombinant human Lp-PLA2. This small molecule plays a significant role in modulating lipid metabolism and inflammatory processes associated with cardiovascular disease. It is valuable for research applications focused on understanding the biological implications of Lp-PLA2 in various pathophysiological conditions.
Lp-PLA2-IN-2 2071636-15-0 Lp-PLA2 Inhibitor
Grouped product items
Size Price Stock Qty
25mg
$1,780.00
In stock
50mg
$2,280.00
In stock
100mg
$2,960.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLp-PLA2-IN-2 is a potent and selective inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), exhibiting an IC50 of 120 nM for recombinant human Lp-PLA2. This small molecule plays a significant role in modulating lipid metabolism and inflammatory processes associated with cardiovascular disease. It is valuable for research applications focused on understanding the biological implications of Lp-PLA2 in various pathophysiological conditions.
Product Information
Catalog NumA77155
FormulaC19H23FN2O4S
Molecular Weight394.46
CAS Number2071636-15-0
SMILESN#CC1=CC(OCCN2C(C[C@@H](C(CC3)(C)CCS3(=O)=O)C2)=O)=CC=C1F
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Metabolism > Phospholipases