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Lp-PLA2-IN-3

Catalog No.: A77134
Phospholipase Inhibitor
Lp-PLA2-IN-3 is a powerful inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), exhibiting an IC50 of 14 nM against recombinant human Lp-PLA2 (rhLpPLA2). This compound demonstrates significant biological activity in modulating inflammation and atherosclerosis-associated pathways. It is applicable in research focused on cardiovascular diseases and other conditions linked to phospholipid metabolism.
Lp-PLA2-IN-3 2196245-16-4 Phospholipase Inhibitor
Grouped product items
Size Price Stock Qty
1mg
$80.00
In stock
2mg
$115.00
In stock
5mg
$195.00
In stock
10mg
$320.00
In stock
25mg
$525.00
In stock
50mg
$725.00
In stock
100mg
$945.00
In stock
500mg
$1,855.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.
Data Sheet SDS

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLp-PLA2-IN-3 is a powerful inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2), exhibiting an IC50 of 14 nM against recombinant human Lp-PLA2 (rhLpPLA2). This compound demonstrates significant biological activity in modulating inflammation and atherosclerosis-associated pathways. It is applicable in research focused on cardiovascular diseases and other conditions linked to phospholipid metabolism.
Product Information
Catalog NumA77134
FormulaC20H13ClF3N3O3S
Molecular Weight467.85
CAS Number2196245-16-4
SMILESO=S(C1=CC=C(N)C=C1)(NC2=CC=C(OC3=CC=C(Cl)C(C(F)(F)F)=C3)C(C#N)=C2)=O
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Metabolism > Phospholipases