Lp-PLA2-IN-6

Catalog No.: A77182
Lp-PLA2 Inhibitor
Lp-PLA2-IN-6 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with an exceptional pIC50 of 10.0 against recombinant human Lp-PLA2. This tetracyclic pyrimidinone compound is primarily utilized in research focusing on neurodegenerative diseases, where its biological activity may contribute to a deeper understanding of disease mechanisms and the development of therapeutic strategies.
Grouped product items
Size Price Stock Qty
25mg
$1,800.00
In stock
50mg
$2,285.00
In stock
100mg
$2,815.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLp-PLA2-IN-6 is a potent inhibitor of lipoprotein-associated phospholipase A2 (Lp-PLA2) with an exceptional pIC50 of 10.0 against recombinant human Lp-PLA2. This tetracyclic pyrimidinone compound is primarily utilized in research focusing on neurodegenerative diseases, where its biological activity may contribute to a deeper understanding of disease mechanisms and the development of therapeutic strategies.
Product Information
Catalog NumA77182
FormulaC25H21F5N4O3
Molecular Weight520.45
CAS Number2637485-13-1
SMILESO=C1N=C(C=C2N1CC34N2C(CC4)CCC3)OCC5=CC(F)=C(C(F)=C5)OC6=CC(C(F)(F)F)=NC=C6
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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