LRRK2-IN-17 is a potent inhibitor of Leucine-rich repeat kinase 2 (LRRK2), with IC50 values of 3.5 nM and 3.3 nM for wild-type and G2019S mutant variants, respectively. Additionally, it exhibits inhibitory activity against RET kinase with an IC50 of 59 nM. This compound is relevant for research applications related to cancer and Parkinson's disease, making it a valuable tool for investigating the role of LRRK2 in these conditions.
LRRK2-IN-17 is a potent inhibitor of Leucine-rich repeat kinase 2 (LRRK2), with IC50 values of 3.5 nM and 3.3 nM for wild-type and G2019S mutant variants, respectively. Additionally, it exhibits inhibitory activity against RET kinase with an IC50 of 59 nM. This compound is relevant for research applications related to cancer and Parkinson's disease, making it a valuable tool for investigating the role of LRRK2 in these conditions.
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