LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 (LSD1) with a Ki value of 11 nM, demonstrating significantly lower affinity for LSD2 (7 μM). This compound effectively inhibits LSD1-mediated cell proliferation, particularly in cancer stem cells, highlighting its potential for oncological research. It is valuable for investigations into epigenetic regulation and therapeutic strategies targeting LSD1 in cancer.
LSD1/2-IN-3 is a selective inhibitor of lysine-specific demethylase 1 (LSD1) with a Ki value of 11 nM, demonstrating significantly lower affinity for LSD2 (7 μM). This compound effectively inhibits LSD1-mediated cell proliferation, particularly in cancer stem cells, highlighting its potential for oncological research. It is valuable for investigations into epigenetic regulation and therapeutic strategies targeting LSD1 in cancer.
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