LSD1/2-IN-4

Catalog No.: A29306
LSD Inhibitor
LSD1/2-IN-4 is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2), exhibiting Ki values of 0.11 μM and 130 μM, respectively. This compound selectively inhibits demethylase activity, making it valuable for studying epigenetic regulation in various biological processes. LSD1/2-IN-4 has potential applications in cancer research, including investigations into T-cell acute lymphoblastic leukemia (TALL), providing insights into therapeutic strategies targeting demethylase pathways.
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5mg
10mg
50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionLSD1/2-IN-4 is an inhibitor of lysine-specific demethylase 1 (LSD1) and lysine-specific demethylase 2 (LSD2), exhibiting Ki values of 0.11 μM and 130 μM, respectively. This compound selectively inhibits demethylase activity, making it valuable for studying epigenetic regulation in various biological processes. LSD1/2-IN-4 has potential applications in cancer research, including investigations into T-cell acute lymphoblastic leukemia (TALL), providing insights into therapeutic strategies targeting demethylase pathways.
Product Information
Catalog NumA29306
FormulaC9H8BrF2N
Molecular Weight248.07
CAS Number2821068-09-9
SMILESN[C@@H]1C[C@H]1C2=CC(F)=C(Br)C(F)=C2
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