LSD1-IN-12 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), exhibiting a Ki value of 1.1 μM for LSD1. Additionally, it demonstrates moderate inhibition of LSD2, MAO-A, and MAO-B with Ki values of 61 μM, 2.3 μM, and 3.5 μM, respectively. This compound is valuable for studying the role of LSD1 in epigenetic regulation and its implications in various diseases, including cancer and neurodegenerative disorders.
LSD1-IN-12 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), exhibiting a Ki value of 1.1 μM for LSD1. Additionally, it demonstrates moderate inhibition of LSD2, MAO-A, and MAO-B with Ki values of 61 μM, 2.3 μM, and 3.5 μM, respectively. This compound is valuable for studying the role of LSD1 in epigenetic regulation and its implications in various diseases, including cancer and neurodegenerative disorders.
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