LSD1-IN-13 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), exhibiting an IC50 of 24.43 nM. This orally active compound has been shown to enhance CD86 expression with an EC50 of 470 nM. Additionally, LSD1-IN-13 promotes differentiation in acute myeloid leukemia (AML) cell lines, making it a valuable tool for investigating epigenetic regulation in cancer research.
LSD1-IN-13 is a potent inhibitor of lysine-specific demethylase 1 (LSD1), exhibiting an IC50 of 24.43 nM. This orally active compound has been shown to enhance CD86 expression with an EC50 of 470 nM. Additionally, LSD1-IN-13 promotes differentiation in acute myeloid leukemia (AML) cell lines, making it a valuable tool for investigating epigenetic regulation in cancer research.
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