LSD1-IN-39 is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) with an IC50 of 0.18 μM. This compound demonstrates significant anti-proliferative effects across various cancer cell lines, effectively inhibits HepG2 cell migration, and prevents epithelial-mesenchymal transition. Furthermore, LSD1-IN-39 exhibits notable antitumor activity in murine models, making it a valuable tool for cancer research.
LSD1-IN-39 is a reversible inhibitor of lysine-specific demethylase 1 (LSD1) with an IC50 of 0.18 μM. This compound demonstrates significant anti-proliferative effects across various cancer cell lines, effectively inhibits HepG2 cell migration, and prevents epithelial-mesenchymal transition. Furthermore, LSD1-IN-39 exhibits notable antitumor activity in murine models, making it a valuable tool for cancer research.
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