LTD4 antagonist 2 is a selective antagonist of leukotriene D4 (LTD4) that exhibits an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R). Additionally, this compound acts as an agonist of G protein-coupled bile acid receptor 1 (GPBAR1). It is valuable for research applications related to inflammatory conditions such as colitis, as well as metabolic syndromes and diseases associated with GPBAR1 and CysLT1R pathways.
LTD4 antagonist 2 is a selective antagonist of leukotriene D4 (LTD4) that exhibits an IC50 of 2.8 μM for the cysteinyl leukotriene 1 receptor (CysLT1R). Additionally, this compound acts as an agonist of G protein-coupled bile acid receptor 1 (GPBAR1). It is valuable for research applications related to inflammatory conditions such as colitis, as well as metabolic syndromes and diseases associated with GPBAR1 and CysLT1R pathways.
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