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Biological Activity
LuAE58054 is a potent and selective 5-HT6 receptor antagonist under development by Lundbeck as an augmentation therapy for the treatment of cognitive deficits associated with Alzheimer's disease and schizophrenia.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23 mL | 114.99 mL | 229.97 mL |
| 0.5 mM | 4.6 mL | 23 mL | 45.99 mL |
| 1 mM | 2.3 mL | 11.5 mL | 23 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
*The above data is based on the productmolecular weight 434.83. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A14356 |
|---|---|
| Actions | Antagonist |
| CAS No. | 467458-02-2 |
| Formula | C20H20ClF5N2O |
| M. Wt | 434.83 |
| Purity | >98% |
| Synonyms | Lu AE58054, Lu AE-58054, Lu AE 58054 |
| SMILES | C1=CC(=CC(=C1)OCC(C(F)F)(F)F)CNCCC2=CNC3=C2C=CC(=C3)F.Cl |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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