Luffariellolide is a potent inhibitor of human synovial fluid phospholipase A2 (HSF-PLA2), with an IC50 value of 5 μM. This compound has demonstrated significant anti-inflammatory activity, evidenced by its ability to effectively inhibit phorbol ester (PMA)-induced ear edema, with an ED50 of 50 μg/ear. Luffariellolide is a valuable tool for research applications focused on inflammation and lipid metabolism.
Luffariellolide is a potent inhibitor of human synovial fluid phospholipase A2 (HSF-PLA2), with an IC50 value of 5 μM. This compound has demonstrated significant anti-inflammatory activity, evidenced by its ability to effectively inhibit phorbol ester (PMA)-induced ear edema, with an ED50 of 50 μg/ear. Luffariellolide is a valuable tool for research applications focused on inflammation and lipid metabolism.
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