Fig. 1 · Structure
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LY 165163
5-HT Receptor Agonist
LY 165163 is a potent agonist of the 5-HT presynaptic receptor. It has been shown to significantly decrease 5-HTP accumulation while increasing DOPA levels in both the cortex and striatum. This compound is useful for studies related to neurotransmitter regulation and the modulation of serotonergic signaling pathways. Research applications include investigations into serotonin-related disorders and their effects on dopamine neurotransmission.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 1814-64-8 |
| Applications | 5-HT Receptor Agonist |
| Formula | C19H22F3N3 |
| Molecular Weight | 349.39 |
| Synonyms | p-NH2-PE-TFMPP |
| SMILES | NC1=CC=C(C=C1)CCN2CCN(CC2)C3=CC=CC(C(F)(F)F)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.