Biological Activity
LY-2584702 tosylate salt is an orally available inhibitor of p70S6K signaling; inhibits p70S6K and prevents phosphorylation of the S6 subunit of ribosomes.
Targets
p70S6K | ||||
4 nM |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 16.19 mL | 80.96 mL | 161.91 mL |
0.5 mM | 3.24 mL | 16.19 mL | 32.38 mL |
1 mM | 1.62 mL | 8.1 mL | 16.19 mL |
5 mM | 0.32 mL | 1.62 mL | 3.24 mL |
*The above data is based on the productmolecular weight 617.62. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15527 |
---|---|
Actions | Inhibitor |
M. Wt | 617.62 |
Formula | C28H27F4N7O3S |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1082949-68-5 |
SMILES | CC1=CC=C(C=C1)S(=O)(=O)O.CN1C=C(N=C1C2CCN(CC2)C3=NC=NC4=C3C=NN4)C5=CC(=C(C=C5)F)C(F)(F)F |
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