LY2365109 hydrochloride

Catalog No.: A21779

GlyT1 inhibitor

LY2365109 hydrochloride

LY2365109 hydrochloride Chemical Structure

CAS NO. 1779796-27-8

LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.

Availability: In stock

Package Price Qty
5 mg
$108.00
10 mg
$186.00
50 mg
$552.00
100 mg
$1,104.00
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Biological Activity

LY2365109 hydrochloride is a potent and selective GlyT1 inhibitor, with an IC50 of 15.8 nM for glycine uptake in cells over-expressing hGlyT1a.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.7 mL 118.51 mL 237.02 mL
0.5 mM 4.74 mL 23.7 mL 47.4 mL
1 mM 2.37 mL 11.85 mL 23.7 mL
5 mM 0.47 mL 2.37 mL 4.74 mL

*The above data is based on the productmolecular weight 421.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21779
Actions Inhibitor
CAS No. 1779796-27-8
Formula C22H28ClNO5
M. Wt 421.91
Purity >98%
Synonyms LY-2365109, LY 2365109
SMILES O=C(O)CN(CCOC1=CC=C(C2=CC=C(OCO3)C3=C2)C=C1C(C)(C)C)C.Cl[H]
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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