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GK activator

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Catalog No. A11406

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY2608204 5mg A11406-5
LY2608204 10mg A11406-10
LY2608204 50mg A11406-50
LY2608204 100mg A11406-100
LY2608204 10mM * 1mL in DMSO A11406-10mM-D

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY2608204 is a potent used to treat type 2 diabetes. In a clinical trial, a study was performed to evaluate the safety and tolerability of LY2608204 in patients with type 2 diabetes.


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Chemical Information

Catalog Num A11406
Actions Activator
M. Wt 559.8
Formula C28H37N3O3S3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1234703-40-2
Synonyms LY-2608204
SMILES C1CCC(CC1)[[email protected]@H]2C[[email protected]@]2(C3=CC=C(C=C3)S(=O)(=O)C4CC4)C(=O)NC5=NC=C(S5)SCCN6CCCC6

Biological Activity

LY2608204 is a potent used to treat type 2 diabetes. In a clinical trial, a study was performed to evaluate the safety and tolerability of LY2608204 in patients with type 2 diabetes.
42 nM(EC50)


Solubility (25°C) * In vitro DMSO 112 mg/mL (200.06 mM)
Water <1 mg/mL (<1 mM)
Ethanol 35 mg/mL (62.52 mM)
In vivo 1% DMSO/30% polyethylene glycol/1% Tween 80 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.86 mL 89.32 mL 178.64mL
0.5 mM 3.57 mL 17.86 mL 35.73 mL
1 mM 1.79 mL 8.93 mL 17.86 mL
5 mM 0.36 mL 1.79 mL 3.57 mL

*The above data is based on the productmolecular weight 559.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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