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Biological Activity
LY2608204 is a potent used to treat type 2 diabetes. In a clinical trial, a study was performed to evaluate the safety and tolerability of LY2608204 in patients with type 2 diabetes.
Targets
glucokinase | ||||
42 nM(EC50) |
In vitro (25°C) | DMSO | 95 mg/mL (169.69 mM) | |
Water | Insoluble | ||
Ethanol | 30 mg/mL (53.59 mM) | ||
In vivo | 1% DMSO+30% polyethylene glycol+1% Tween 80 | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.86 mL | 89.32 mL | 178.64 mL |
0.5 mM | 3.57 mL | 17.86 mL | 35.73 mL |
1 mM | 1.79 mL | 8.93 mL | 17.86 mL |
5 mM | 0.36 mL | 1.79 mL | 3.57 mL |
*The above data is based on the productmolecular weight 559.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11406 |
---|---|
Actions | Activator |
CAS No. | 1234703-40-2 |
Formula | C28H37N3O3S3 |
M. Wt | 559.8 |
Purity | >98% |
Synonyms | LY-2608204 |
SMILES | C1CCC(CC1)[[email protected]@H]2C[[email protected]@]2(C3=CC=C(C=C3)S(=O)(=O)C4CC4)C(=O)NC5=NC=C(S5)SCCN6CCCC6 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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