LY2835219 methanesulfonate

Catalog No.: A16386

CDK4/6 inhibitor

LY2835219 methanesulfonate Chemical Structure

CAS NO. 1231930-82-7

LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.

Availability: In stock

Package Price Qty
5 mg
$50.00
10 mg
$90.00
50 mg
$110.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY2835219 is a potent and selective inhibitor of CDK4 and CDK6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively. Phase 3.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.59 mL 82.96 mL 165.92 mL
0.5 mM 3.32 mL 16.59 mL 33.18 mL
1 mM 1.66 mL 8.3 mL 16.59 mL
5 mM 0.33 mL 1.66 mL 3.32 mL

*The above data is based on the productmolecular weight 602.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16386
Actions Inhibitor
M. Wt 602.7
Formula C27H32F2N8.CH4O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1231930-82-7
Synonyms Abemaciclib
SMILES CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O

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