2018-2019 AdooQ Catalog Book Available Click here to download
Trusted by 10,000+ Scientists since 2006

LY315920 (Varespladib)

ON SALE

HnsPLA inhibitor

0 Customer Reviews
Catalog No. A10548

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY315920 5mg A10548-5

Regular Price: $60.00

Special Price: $54.00

LY315920 10mg A10548-10

Regular Price: $110.00

Special Price: $99.00

LY315920 50mg A10548-50

Regular Price: $330.00

Special Price: $297.00

LY315920 100mg A10548-100

Regular Price: $550.00

Special Price: $495.00

LY315920 (Varespladib) 10mM * 1mL in DMSO A10548-10mM-D

Regular Price: $60.00

Special Price: $54.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY315920 (Varespladib) is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2).

LY315920 (Varespladib)

Double click on above image to view full picture

Zoom Out
Zoom In

More Views

Publications citing Adooq Products
LY315920 (Varespladib) Citations (2)
  • Yap WH,et al. Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells, Mol Cell Biochem, 2018, Oct;447(1-2):93-101 29374817
  • Yamato Okita,et al. Interleukin-22-Induced Antimicrobial Phospholipase A2 Group IIA Mediates Protective Innate Immunity of Nonhematopoietic Cells against Listeria monocytogenes, Infect Immun, 2016, Feb; 84(2): 573-579 26644377

Chemical Information

Catalog Num A10548
Actions Inhibitor
M. Wt 380.4
Formula C21H20N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 172732-68-2
Synonyms LY-315920, S-5920
SMILES code CCC1=C(C2=C(N1CC3=CC=CC=C3)C=CC=C2OCC(=O)O)C(=O)C(=O)N
Chemical Name 2-[2-ethyl-3-oxamoyl-1-(phenylmethyl)indol-4-yl]oxyacetic acid

Biological Activity

Description
LY315920 (Varespladib) is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2).
Targets
hnsPLA2
7 nM

Solubility

Solubility (25°C) * In vitro DMSO 76 mg/mL (199.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.29 mL 131.44 mL 262.88mL
0.5 mM 5.26 mL 26.29 mL 52.58 mL
1 mM 2.63 mL 13.14 mL 26.29 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

View Related Products By Research Topics

Ordering online

To place an order online, simply browse to the product you are interested in and click on the 'Add to Cart' button. To complete this process, you will need to confirm the size and quantity of the products that you require.

To complete an order you will need to register using our simple online registration process. We do not share your contact details with any third parties.

When you are ready to check out simply enter your PO number to complete the ordering process. Please ensure that you send us a copy of your PO by fax or email afterwards.  We will then liaise with you or your purchasing department to confirm the order.

Found your products but not ready to order?

Why not use our WishList feature to store lists of products? This convenient feature allows you to manage lists, append notes to products and share lists with co-workers or colleagues.

Ordering offline

You can email or fax us your purchase order and we will place the order for you. You can also phone us to place the order.  Our contact details are:

We require the following information to process your order:
  • The catalog number for each product. 
  • Your email address or fax number. 
  • Your name and telephone number. 
  • Shipping address and billing address.
  • Purchase order numbers.

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.


Keywords:buy LY315920 (Varespladib) | LY315920 (Varespladib) Supplier | purchase LY315920 (Varespladib) | LY315920 (Varespladib) cost | LY315920 (Varespladib) manufacturer | order LY315920 (Varespladib) | LY315920 (Varespladib) distributor | buy 172732-68-2| 172732-68-2 Supplier | purchase 172732-68-2 | 172732-68-2 cost | 172732-68-2 manufacturer | order 172732-68-2 | 172732-68-2 distributor