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LY315920 (Varespladib)


HnsPLA inhibitor

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Catalog No. A10548

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LY315920 5mg A10548-5

Regular Price: $60.00

Special Price: $54.00

LY315920 10mg A10548-10

Regular Price: $110.00

Special Price: $99.00

LY315920 50mg A10548-50

Regular Price: $330.00

Special Price: $297.00

LY315920 100mg A10548-100

Regular Price: $550.00

Special Price: $495.00

LY315920 (Varespladib) 10mM * 1mL in DMSO A10548-10mM-D

Regular Price: $60.00

Special Price: $54.00

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LY315920 (Varespladib) is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2).

LY315920 (Varespladib)

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Publications citing Adooq Products
LY315920 (Varespladib) Citations (2)
  • Yap WH, .et al. Differential effects of sPLA2-GV and GX on cellular proliferation and lipid accumulation in HT29 colon cancer cells, Mol Cell Biochem, 2018, Oct;447(1-2):93-101 PMID: 29374817
  • Yamato Okita, .et al. Interleukin-22-Induced Antimicrobial Phospholipase A2 Group IIA Mediates Protective Innate Immunity of Nonhematopoietic Cells against Listeria monocytogenes, Infect Immun, 2016, Feb; 84(2): 573-579 PMID: 26644377

Chemical Information

Catalog Num A10548
Actions Inhibitor
M. Wt 380.4
Formula C21H20N2O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 172732-68-2
Synonyms LY-315920, S-5920

Biological Activity

LY315920 (Varespladib) is an inhibitor of the IIa, V, and X isoforms of secretory phospholipase A2 (sPLA2).
7 nM


Solubility (25°C) * In vitro DMSO 76 mg/mL (199.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.29 mL 131.44 mL 262.88mL
0.5 mM 5.26 mL 26.29 mL 52.58 mL
1 mM 2.63 mL 13.14 mL 26.29 mL
5 mM 0.53 mL 2.63 mL 5.26 mL

*The above data is based on the productmolecular weight 380.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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