LY341495

Catalog No.: A11484

mGluR-2 antagonist

LY341495

LY341495 Chemical Structure

CAS NO. 201943-63-7

LY 341495 has been shown to be a highly potent and selective group II metabotropic glutamate receptor (mGluR-2) antagonist with Ki / IC50 values are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGluR-2, mGluR-3, mGluR-8 , mGluR-7a, mGluR-1a, mGluR-5a and mGluR-4a.

Availability: Out of stock

Package Price
10 mg
$60.00
25 mg
$120.00
50 mg
$200.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY 341495 has been shown to be a highly potent and selective group II metabotropic glutamate receptor (mGluR-2) antagonist with Ki / IC50 values are 2.3, 1.3, 173, 990, 6800, 8200 and 22000 nM for human mGluR-2, mGluR-3, mGluR-8 , mGluR-7a, mGluR-1a, mGluR-5a and mGluR-4a.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.3 mL 141.49 mL 282.99 mL
0.5 mM 5.66 mL 28.3 mL 56.6 mL
1 mM 2.83 mL 14.15 mL 28.3 mL
5 mM 0.57 mL 2.83 mL 5.66 mL

*The above data is based on the productmolecular weight 353.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11484
Actions Antagonist
M. Wt 353.37
Formula C20H19NO5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 201943-63-7
Synonyms N/A
SMILES C1[[email protected]@H]([[email protected]]1[[email protected]@](CC2C3=CC=CC=C3OC4=CC=CC=C24)(C(=O)O)N)C(=O)O

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