Macbecin I

Catalog No.: A16050

HSP90 inhibitor

Macbecin I

Macbecin I Chemical Structure

CAS NO. 73341-72-7

Macbecin I is an ansamycin antibiotic compound that inhibits Hsp90 activity with IC50 value of μM by binding to the ATP-binding site.

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1 mg
$200.00
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Biological Activity

Macbecin I is an ansamycin antibiotic compound that inhibits Hsp90 activity with IC50 value of μM by binding to the ATP-binding site.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.9 mL 89.5 mL 179 mL
0.5 mM 3.58 mL 17.9 mL 35.8 mL
1 mM 1.79 mL 8.95 mL 17.9 mL
5 mM 0.36 mL 1.79 mL 3.58 mL

*The above data is based on the productmolecular weight 558.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16050
Actions Inhibitor
CAS No. 73341-72-7
Formula C30H42N2O8
M. Wt 558.67
Solubility DMSO
Purity >98%
SMILES O=C(C(NC1=O)=C2)C([[email protected]@H]([[email protected]@H](C)C[[email protected]]([[email protected]]([[email protected]](C)/C=C(C)/[[email protected]]([[email protected]](/C=C\C=C1/C)C)OC(N)=O)OC)OC)OC)=CC2=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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