MAGL Ligand-Linker Conjugate 1

Catalog No.: A80086
MAGL Ligand-Linker Conjugate
MAGL Ligand-Linker Conjugate 1 is a conjugate designed to target monoacylglycerol lipase (MAGL) through its ligand-linker structure. This reagent serves as an essential component for the synthesis of PROTAC MAGL degrader-1, facilitating targeted protein degradation in research applications focused on MAGL inhibition. Its utility extends to studies involving lipid metabolism and related signaling pathways.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMAGL Ligand-Linker Conjugate 1 is a conjugate designed to target monoacylglycerol lipase (MAGL) through its ligand-linker structure. This reagent serves as an essential component for the synthesis of PROTAC MAGL degrader-1, facilitating targeted protein degradation in research applications focused on MAGL inhibition. Its utility extends to studies involving lipid metabolism and related signaling pathways.
Product Information
Catalog NumA80086
FormulaC28H28N2O9
Molecular Weight536.53
CAS Number2725023-11-8
SMILESOCCOC1=CC=C(C(C2CCN(C(OC3=CC=C([N+]([O-])=O)C=C3)=O)CC2)(O)C4=CC=C(OCO5)C5=C4)C=C1
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