Mal-amide-PEG4-Val-Cit-PAB-OH

Catalog No.: A42916
ADC Linker
Mal-amide-PEG4-Val-Cit-PAB-OH is a cleavable linker featuring a Maleimide group, primarily used in the synthesis of antibody-drug conjugates (ADCs). This linker facilitates the conjugation of therapeutic agents to antibodies, ensuring targeted delivery in cancer research and therapeutic applications. Its design allows for precise cleavage in the tumor environment, enhancing the efficacy and reducing off-target effects of ADCs.
Grouped product items
Size Price Stock Qty
5mg
$90.00
In stock
10mg
$135.00
In stock
25mg
$250.00
In stock
50mg
$370.00
In stock
100mg
$545.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-amide-PEG4-Val-Cit-PAB-OH is a cleavable linker featuring a Maleimide group, primarily used in the synthesis of antibody-drug conjugates (ADCs). This linker facilitates the conjugation of therapeutic agents to antibodies, ensuring targeted delivery in cancer research and therapeutic applications. Its design allows for precise cleavage in the tumor environment, enhancing the efficacy and reducing off-target effects of ADCs.
Product Information
Catalog NumA42916
FormulaC36H55N7O12
Molecular Weight777.86
CAS Number1949793-41-2
SMILESOCC1=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN2C(C=CC2=O)=O)=O)=O)=O)=O)C=C1
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