Mal-Cyclohexyl-PEG3-Biotin is a bioconjugation reagent featuring a maleimide functionality for specific reactions with sulfhydryl groups, forming stable thioether linkages under mild pH conditions (6.5-7.5). This reagent enables biotinylation of amine-containing molecules when paired with coupling agents such as EDC or HATU. The PEG component introduces a flexible spacer, enhancing the accessibility of biotin to protein binding sites, while significantly improving the solubility of the biotin-PEG conjugates, making it an invaluable tool for biochemical assays and protein labeling applications.
Mal-Cyclohexyl-PEG3-Biotin is a bioconjugation reagent featuring a maleimide functionality for specific reactions with sulfhydryl groups, forming stable thioether linkages under mild pH conditions (6.5-7.5). This reagent enables biotinylation of amine-containing molecules when paired with coupling agents such as EDC or HATU. The PEG component introduces a flexible spacer, enhancing the accessibility of biotin to protein binding sites, while significantly improving the solubility of the biotin-PEG conjugates, making it an invaluable tool for biochemical assays and protein labeling applications.
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