Mal-PEG2-Val-Cit-PABA is a cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents within target cells, enhancing therapeutic efficacy while minimizing off-target effects. Its structure promotes stability during circulation and triggers cleavage in the presence of specific intracellular conditions, making it a valuable tool for ADC development and research applications in cancer treatment.
Mal-PEG2-Val-Cit-PABA is a cleavable linker designed for the synthesis of antibody-drug conjugates (ADCs). This compound facilitates the selective release of cytotoxic agents within target cells, enhancing therapeutic efficacy while minimizing off-target effects. Its structure promotes stability during circulation and triggers cleavage in the presence of specific intracellular conditions, making it a valuable tool for ADC development and research applications in cancer treatment.
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