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Mal-PEG4-VA-PBD

Catalog No.: A41357
Drug-Linker Conjugate for ADC
Mal-PEG4-VA-PBD is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It utilizes the potent antitumor antibiotic Pyrrolobenzodiazepine (PBD), which is covalently linked through Mal-PEG4-VA. This compound facilitates targeted delivery of PBD to tumor cells, enhancing therapeutic efficacy while minimizing off-target effects. Mal-PEG4-VA-PBD is ideal for research into ADC development and optimization in cancer therapy.
Mal-PEG4-VA-PBD 1342820-68-1 Drug-Linker Conjugate for ADC
Grouped product items
Size Price Stock Qty
1mg
$870.00
In stock
5mg
$1,925.00
In stock
10mg
$3,160.00
In stock
25mg
$8,215.00
In stock
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMal-PEG4-VA-PBD is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications. It utilizes the potent antitumor antibiotic Pyrrolobenzodiazepine (PBD), which is covalently linked through Mal-PEG4-VA. This compound facilitates targeted delivery of PBD to tumor cells, enhancing therapeutic efficacy while minimizing off-target effects. Mal-PEG4-VA-PBD is ideal for research into ADC development and optimization in cancer therapy.
Product Information
Catalog NumA41357
FormulaC68H79N9O17
Molecular Weight1294.40
CAS Number1342820-68-1
SMILES[H][C@]12N(C(C3=CC(OC)=C(OCCCOC4=C(C=C5C(N=C[C@@]6([H])N(C=C(C7=CC=C(OC)C=C7)C6)C5=O)=C4)OC)C=C3N=C2)=O)C=C(C8=CC=C(NC([C@H](C)NC([C@H](C(C)C)NC(CCOCCOCCOCCOCCNC(CCN9C(C=CC9=O)=O)=O)=O)=O)=O)C=C8)C1
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Antibody-drug Conjugates (ADC) > Drug-Linker Conjugates for ADC