Maleimido-tri(ethylene glycol)-propionic acid is a cleavable linker designed for use in antibody-drug conjugates (ADCs). It facilitates the synthesis of neolymphostin-based ADC precursors, enabling site-specific conjugation to cysteine mutant trastuzumab-A114C. Additionally, this compound serves as a PEG-based linker in the development of PROTACs, contributing to research in targeted protein degradation and therapeutic applications.
Maleimido-tri(ethylene glycol)-propionic acid is a cleavable linker designed for use in antibody-drug conjugates (ADCs). It facilitates the synthesis of neolymphostin-based ADC precursors, enabling site-specific conjugation to cysteine mutant trastuzumab-A114C. Additionally, this compound serves as a PEG-based linker in the development of PROTACs, contributing to research in targeted protein degradation and therapeutic applications.
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