MAO-B-IN-10

Catalog No.: A78344
MAO-B Inhibitor
MAO-B-IN-10 is a selective monoamine oxidase B (MAO-B) inhibitor with a potent IC50 of 5.3 μM. It effectively inhibits and disaggregates amyloid β (Aβ) aggregation, achieving 58.2% inhibition and 43.3% disaggregation of self-mediated Aβ. This compound is valuable for research related to Alzheimer's disease, offering insights into the modulation of Aβ aggregation in neurodegenerative processes.
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5mg
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50mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMAO-B-IN-10 is a selective monoamine oxidase B (MAO-B) inhibitor with a potent IC50 of 5.3 μM. It effectively inhibits and disaggregates amyloid β (Aβ) aggregation, achieving 58.2% inhibition and 43.3% disaggregation of self-mediated Aβ. This compound is valuable for research related to Alzheimer's disease, offering insights into the modulation of Aβ aggregation in neurodegenerative processes.
Product Information
Catalog NumA78344
FormulaC23H26N2O4
Molecular Weight394.46
CAS Number2376710-36-8
SMILESCCN(C(OC1=C(C=C(C=C1)/C=C/C(N2CCC3=C(C2)C=CC=C3)=O)OC)=O)C
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