MAO-B-IN-15 is a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 13.5 μM, demonstrating its ability to effectively inhibit enzymatic activity through π-π interactions with the Tyr 326 residue. This compound is integral for research focused on neurodegenerative disorders, particularly Parkinson's disease, by potentially enhancing dopaminergic neurotransmission and reducing oxidative stress associated with neuronal degeneration.
MAO-B-IN-15 is a selective inhibitor of monoamine oxidase B (MAO-B), with an IC50 value of 13.5 μM, demonstrating its ability to effectively inhibit enzymatic activity through π-π interactions with the Tyr 326 residue. This compound is integral for research focused on neurodegenerative disorders, particularly Parkinson's disease, by potentially enhancing dopaminergic neurotransmission and reducing oxidative stress associated with neuronal degeneration.
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