MAO-B-IN-37

Catalog No.: A79024
MAO-B Inhibitor
MAO-B-IN-37 is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting an IC50 value of 270 nM. This compound demonstrates favorable metabolic stability in mouse microsomes, along with strong binding affinity to human serum albumin. It is valuable for research applications focused on neurological disorders and oxidative stress, where modulation of MAO-B activity may provide therapeutic insights.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMAO-B-IN-37 is a selective inhibitor of monoamine oxidase B (MAO-B), exhibiting an IC50 value of 270 nM. This compound demonstrates favorable metabolic stability in mouse microsomes, along with strong binding affinity to human serum albumin. It is valuable for research applications focused on neurological disorders and oxidative stress, where modulation of MAO-B activity may provide therapeutic insights.
Product Information
Catalog NumA79024
FormulaC14H12FN3O3
Molecular Weight289.26
CAS Number894280-02-5
SMILESO=C(NCC1=CC=C(F)C=C1)NC2=CC=C([N+]([O-])=O)C=C2
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