MAO-B-IN-47 is a selective inhibitor of monoamine oxidase B (MAO-B) with a Ki of 875 nM. This compound demonstrates neuroprotective effects in SH-SY5Y cells treated with 6-hydroxydopamine (6-OHDA), showing an IC50 greater than 100 μM. MAO-B-IN-47 is valuable for research into neurological disorders, particularly Parkinson's disease, by potentially mitigating neuronal damage associated with MAO-B activity.
MAO-B-IN-47 is a selective inhibitor of monoamine oxidase B (MAO-B) with a Ki of 875 nM. This compound demonstrates neuroprotective effects in SH-SY5Y cells treated with 6-hydroxydopamine (6-OHDA), showing an IC50 greater than 100 μM. MAO-B-IN-47 is valuable for research into neurological disorders, particularly Parkinson's disease, by potentially mitigating neuronal damage associated with MAO-B activity.
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