MAO-B-IN-9 is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) that effectively penetrates the blood-brain barrier, exhibiting an IC50 of 0.18 μM. This compound demonstrates neuroprotective effects by preventing Aβ1-42-induced neuronal cell death, potentially through its ability to inhibit Aβ1-42 aggregation. Additionally, MAO-B-IN-9 serves as a click chemistry reagent, featuring an alkyne group that readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions for versatile applications in chemical biology research.
MAO-B-IN-9 is a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) that effectively penetrates the blood-brain barrier, exhibiting an IC50 of 0.18 μM. This compound demonstrates neuroprotective effects by preventing Aβ1-42-induced neuronal cell death, potentially through its ability to inhibit Aβ1-42 aggregation. Additionally, MAO-B-IN-9 serves as a click chemistry reagent, featuring an alkyne group that readily participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions for versatile applications in chemical biology research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
