MC180295

Name: MC180295
SKU: A18892
Price: 180 USD
Rating: 5 (288 reviews)

Catalog No.: A18892

CDK9 inhibitor

MC180295 is a highly selective CDK9 inhibitor (IC50 = 5 nM). MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.

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Grouped product items
Product Name	Price	Stock
MC180295 1mg	$180.00	In stock
MC180295 5mg	$620.00	In stock
MC180295 10mg	$900.00	In stock
MC180295 50mg	$2,700.00	In stock
Bulk Size	Bulk Discount

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Data Sheet

SDS

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Biological Activity

Discription

MC180295 is a highly selective CDK9 inhibitor (IC50 = 5 nM). MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.

Targets

Target	Value

Product Information

Catalog Num	A18892
Formula	C17H18N4O3S
Molecular Weight	358.41
CAS Number	2237942-08-2
SMILES	O=C(C1=C(N)N=C(N[C@@H]2C(C3)CCC3C2)S1)C4=CC=CC=C4[N+]([O-])=O
Synonyms	MC180295; MC-180295; MC 180295;
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro	DMSO	64 mg/mL (178.56 mM)
	Water	64 mg/mL (178.56 mM)
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.9 mL	139.51 mL	279.01 mL
0.5 mM	5.58 mL	27.9 mL	55.8 mL
1 mM	2.79 mL	13.95 mL	27.9 mL
5 mM	0.56 mL	2.79 mL	5.58 mL

Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂