MC180295

Catalog No.: A18892

CDK9 inhibitor

MC180295

MC180295 Chemical Structure

CAS NO. 2237942-08-2

MC180295 is a highly selective CDK9 inhibitor (IC50 = 5 nM). MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.

Availability: In stock

Package Price Qty
1 mg
$180.00
5 mg
$620.00
10 mg
$900.00
50 mg
$2,700.00
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Biological Activity

MC180295 is a highly selective CDK9 inhibitor (IC50 = 5 nM). MC180295 also inhibits GSK-3α and GSK-3β. MC180295 ((rel)-MC180295) has potent anti-tumor effect.
In vitro DMSO 64 mg/mL (178.56 mM)
Water 64 mg/mL (178.56 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.9 mL 139.51 mL 279.01 mL
0.5 mM 5.58 mL 27.9 mL 55.8 mL
1 mM 2.79 mL 13.95 mL 27.9 mL
5 mM 0.56 mL 2.79 mL 5.58 mL

*The above data is based on the productmolecular weight 358.41. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18892
Actions Inhibitor
CAS No. 2237942-08-2
Formula C17H18N4O3S
M. Wt 358.41
Purity >98%
Synonyms MC180295; MC-180295; MC 180295;
SMILES O=C(C1=C(N)N=C(N[[email protected]@H]2C(C3)CCC3C2)S1)C4=CC=CC=C4[N+]([O-])=O
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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