MCAAD-3 is a near-infrared imaging probe designed to target amyloid-beta (Aβ) species, facilitating visualization of Aβ plaques in vivo. It possesses exceptional affinity for Aβ polymers, with a dissociation constant (Ki) exceeding 106 nM. This probe effectively permeates the blood-brain barrier, making it a valuable tool for studying Alzheimer’s disease and related neurodegenerative conditions in transgenic mouse models.
MCAAD-3 is a near-infrared imaging probe designed to target amyloid-beta (Aβ) species, facilitating visualization of Aβ plaques in vivo. It possesses exceptional affinity for Aβ polymers, with a dissociation constant (Ki) exceeding 106 nM. This probe effectively permeates the blood-brain barrier, making it a valuable tool for studying Alzheimer’s disease and related neurodegenerative conditions in transgenic mouse models.
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