MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2) with an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. It demonstrates strong affinity for both human and rat CB2 receptors, indicated by Ki values of 422 nM and 238 nM, respectively. MDA7 exhibits notable analgesic effects in rat models, making it a valuable tool for researching cannabinoid signaling and pain modulation.
MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2) with an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. It demonstrates strong affinity for both human and rat CB2 receptors, indicated by Ki values of 422 nM and 238 nM, respectively. MDA7 exhibits notable analgesic effects in rat models, making it a valuable tool for researching cannabinoid signaling and pain modulation.
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