Me-Thalidomide-O-C8-NH2

Catalog No.: A80131
E3 Ligase Ligand-Linker Conjugate
Me-Thalidomide-O-C8-NH2 is an E3 ligase ligand-linker conjugate that facilitates targeted protein degradation. This compound demonstrates key biological activity in modulating E3 ubiquitin ligase interactions, which is essential for the development of novel therapeutic strategies. It serves as a valuable intermediate in the synthesis of MS154N, contributing to research in drug discovery and cellular regulation pathways.
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionMe-Thalidomide-O-C8-NH2 is an E3 ligase ligand-linker conjugate that facilitates targeted protein degradation. This compound demonstrates key biological activity in modulating E3 ubiquitin ligase interactions, which is essential for the development of novel therapeutic strategies. It serves as a valuable intermediate in the synthesis of MS154N, contributing to research in drug discovery and cellular regulation pathways.
Product Information
Catalog NumA80131
FormulaC22H29N3O5
Molecular Weight415.48
CAS Number2550393-20-7
SMILESNCCCCCCCCOC1=CC=CC(C2=O)=C1C(N2C3C(N(C)C(CC3)=O)=O)=O
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