Fig. 1 · Structure
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Melatonin-d4
Stable Isotope
Melatonin-d4 is a deuterium-labeled derivative of the hormone melatonin, primarily known for activating melatonin receptors. It exhibits antioxidative and anti-inflammatory properties, making it valuable in various biochemical research applications. Additionally, Melatonin-d4 serves as a selective inhibitor of ATF-6, inducing apoptosis in human hepatoma cells through the downregulation of COX-2. This reagent is useful for studying cellular mechanisms related to melatonin and its derivatives in therapeutic contexts.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 66521-38-8 |
| Applications | Stable Isotope |
| Formula | C13H12D4N2O2 |
| Molecular Weight | 236.30 |
| Synonyms | N-Acetyl-5-methoxytryptamine-d4 |
| SMILES | CC(NC([2H])([2H])C([2H])([2H])C1=CNC2=C1C=C(OC)C=C2)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.