meso-Tetra(4-pyridyl)porphine

Catalog No.: A57116
Top1 Inhibitor
meso-Tetra(4-pyridyl)porphine is a porphyrin derivative that acts as a weak inhibitor of human topoisomerase I (Top1), with an EC50 value exceeding 50 µM. This compound is of interest in tumor research, enabling investigations into the role of Top1 in cancer biology and potential therapeutic strategies. Its unique structural features make it a valuable tool for studying topoisomerase-related mechanisms in cellular processes.
Grouped product items
Size Price Stock Qty
250mg
$25.00
In stock
500mg
$45.00
In stock
1g
$70.00
In stock
5g
$170.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
Descriptionmeso-Tetra(4-pyridyl)porphine is a porphyrin derivative that acts as a weak inhibitor of human topoisomerase I (Top1), with an EC50 value exceeding 50 µM. This compound is of interest in tumor research, enabling investigations into the role of Top1 in cancer biology and potential therapeutic strategies. Its unique structural features make it a valuable tool for studying topoisomerase-related mechanisms in cellular processes.
Product Information
Catalog NumA57116
FormulaC40H26N8
Molecular Weight618.70
CAS Number16834-13-2
SMILESC1(/C2=CC=NC=C2)=C3C=CC(/C(C4=CC=NC=C4)=C5C=C/C(N/5)=C(C6=CC=NC=C6)/C(C=C/7)=NC7=C(C8=CC=NC=C8)/C9=CC=C1N9)=N/3
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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